Novel Work Informs How a Cell Pathway Activates Innate Immunity

Different pathways within the cell are activated or silenced dependent on the external signals acting on a cell. One such pathway includes the stimulator of interferon genes (STING) pathway which acts as a mediator of inflammation in the context of cell stress and tissue damage. This pathway is activated through external signals after foreign molecule detection, however long-term inflammatory induction can lead to disease. Several inflammatory diseases including autoimmune disorders and cancer are associated with upregulation of the STING pathway. Thus,…